Effect of mango butter on the physicochemical properties of beeswax-Moringa seed oil-based oleogels for topical application.
Drug Dev Ind Pharm
; 50(5): 432-445, 2024 May.
Article
em En
| MEDLINE
| ID: mdl-38526993
ABSTRACT
OBJECTIVE:
The purpose of this research was to determine any connections between the characteristics of oleogels made of beeswax and the impact of mango butter.METHODS:
Oleogel was prepared through inverted tube methods, and optimized through oil binding capacity. Other evaluations like bright field and polarized microscopy, Fourier-transform infrared (FTIR) spectroscopy, crystallization kinetics, mechanical study, and X-ray diffractometry (XRD). The drug release kinetic studies and in vitro antibacterial studies were performed.RESULTS:
FTIR study reveals that the gelation process does not significantly alter the chemical composition of the individual components. Prepared gel exhibiting fluid-like behavior or composed of brittle networks is particularly vulnerable to disruptions in their network design. The incorporation of mango butter increases the drug permeation. In-vitro microbial efficacy study was found to be excellent.CONCLUSION:
The studies revealed that mango butter can be used to modify the physico-chemical properties of the oleogels.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Compostos Orgânicos
/
Ceras
/
Óleos de Plantas
/
Mangifera
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article