Estimation of internal-exposure contribution in radiation dose exposure for boron neutron capture therapy.
Radiat Prot Dosimetry
; 200(7): 623-628, 2024 May 08.
Article
em En
| MEDLINE
| ID: mdl-38527175
ABSTRACT
Although boron neutron capture therapy (BNCT) causes minor damage to normal cells owing to the nuclear reactions induced by neutrons with major elements of tissues such as hydrogen and nitrogen, it is useful to estimate the accurate exposure dose for radiation protection. This study aims to estimate the contribution of internal exposure in radiation exposure dose for BNCT. The study was performed by referring to clinical studies at a reactor-based BNCT facility on the basis of computational dosimetry. Five irradiation regions of head and neck were selected for the estimation. The results suggest that external exposure occurred primarily in and around the irradiation field. Furthermore, during the exposure dose estimation in BNCT, internal exposure was found to be not negligible, implying that the irradiation regions in treatment planning must be considered for avoiding damage to certain critical organs that are susceptible to internal exposure.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Terapia por Captura de Nêutron de Boro
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article