A study on the treatment of brain tumors with BNCT using several moderators with different thicknesses.
Appl Radiat Isot
; 208: 111303, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38531243
ABSTRACT
Boron neutron capture therapy (BNCT) is an effective binary radiation therapy that depends on nuclear capture reactions. In recent years, BNCT can be performed without a reactor owing to the development of accelerator-based neutron sources. A new BNCT irradiation facility is proposed, which is based on a 15 mA 2.5 MeV proton accelerator with a 100 µm thickness natural lithium target as a neutron converter. A great quantity of studies has shown that neutron beams with different spectra have unique therapeutic effects on tumors. An appropriate neutron beam for BNCT is obtained by Beam Shaping Assembly (BSA) and the moderator plays a main role in determining the BSA outlet beam spectrum. To figure out the dose distribution in phantom with various kinds of neutron spectrum modes during BNCT, a series of cases are calculated by MCNPX code. The results give a database for treatment of brain tumors with BNCT by using different moderators.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Encefálicas
/
Terapia por Captura de Nêutron de Boro
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article