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Predictors of Outcome after Direct Aspiration of Basilar Artery Occlusion.
Mako, Miroslav; Krastev, Georgi; Nosál, Vladimír; Haring, Jozef; Jakubcová, Denisa; Danis, Martin; Klepanec, Andrej; Harsány, Ján; Sivák, Stefan; Kurca, Egon.
Afiliação
  • Mako M; Department of Neurology, Faculty Hospital Trnava, 91701 Trnava, Slovakia.
  • Krastev G; Slovak Medical University, Limbová 12, 83303 Bratislava, Slovakia.
  • Nosál V; Department of Neurology, Faculty Hospital Trnava, 91701 Trnava, Slovakia.
  • Haring J; Slovak Medical University, Limbová 12, 83303 Bratislava, Slovakia.
  • Jakubcová D; Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 03659 Martin, Slovakia.
  • Danis M; Clinic of Neurology, University Hospital Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, 03659 Martin, Slovakia.
  • Klepanec A; Department of Neurology, Faculty Hospital Trnava, 91701 Trnava, Slovakia.
  • Harsány J; Slovak Medical University, Limbová 12, 83303 Bratislava, Slovakia.
  • Sivák S; Medical Faculty, Comenius University, 81372 Bratislava, Slovakia.
  • Kurca E; Faculty of Health Care and Social Work, Trnava University, 91843 Trnava, Slovakia.
J Clin Med ; 13(6)2024 Mar 09.
Article em En | MEDLINE | ID: mdl-38541802
ABSTRACT

Background:

Basilar artery occlusion (BAO) is a serious disease with a poor prognosis if left untreated. Endovascular therapy (EVT) is the most effective treatment that is able to reduce mortality and disability. Treatment results are influenced by a wide range of factors that have not been clearly identified. In the present study, direct aspiration was chosen as a first-line treatment. The safety and effectiveness of direct aspiration in BAO were determined, and factors affecting patient outcomes were identified.

Methodology:

Data for patients with BAO treated between November 2013 and December 2021 were evaluated using a database. The association between clinical and procedural parameters and functional outcome was assessed.

Results:

A total of 89 patients with BAO were identified. Full recanalization was achieved in 69.7% of cases and partial recanalization in 19.1%. Intracranial hemorrhage was detected in 11 (12.4%) patients, of which, eight (9.0%) patients experienced symptomatic intracranial hemorrhage. Patients with good outcomes presented with milder strokes (mean NIHSS score of 12.58 vs. 24.00, p < 0.001), had higher collateral scores (6.79 vs. 5.88, p = 0.016), more often achieved complete recanalization (87.9% vs. 58.9%, p = 0.009), and more often experienced early neurological improvement (66.7% vs. 26.8%, p < 0.001). On the contrary, patients with worse outcomes had higher serum glucose levels (p = 0.05), occlusion of the middle portion of the basilar artery (MAB) (30.3% vs. 53.6%, p = 0.033), longer thrombus lengths (10.51 vs. 16.48 mm, p = 0.046), and intracranial hemorrhage (p = 0.035).

Conclusions:

The present study results suggest that direct aspiration is a safe and effective treatment for patients with BAO. We identified several factors affecting the patients' outcome.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article