Are behavioral interventions a better choice for atopic dermatitis patients? A meta-analysis of 6 randomized controlled trials.
An Bras Dermatol
; 99(4): 503-512, 2024.
Article
em En
| MEDLINE
| ID: mdl-38548550
ABSTRACT
BACKGROUND:
The treatment for atopic dermatitis (AD) has been the focus of clinical research, and behavioral intervention is considered an indispensable treatment method. To our knowledge, no relevant meta-analysis has evaluated the effects of behavioral interventions on atopic dermatitis.OBJECTIVES:
To evaluate the effects of behavioral interventions on atopic dermatitis.METHODS:
The authors searched PubMed, EMBASE, and Cochrane CENTRAL to retrieve relevant RCTs (up to Feb 2022). The search strategy involved a combination of related keywords. The Cochrane Q and I2 statistics were used to assess heterogeneity.RESULTS:
Six RCTs involving seven reports with 246 patients were included. The results suggested that behavioral interventions could relieve eczema severity (correlation coefficient [r = -0.39]; pâ¯<â¯0.001) and scratching severity significantly (r = -0.19; pâ¯=â¯0.017), while not affect itching intensity (r = -0.02; pâ¯=â¯0.840). A sensitivity analysis confirmed the robustness of the results. STUDYLIMITATIONS:
An important limitation of this study was the insufficient number of RCTs and the limited sample size. In addition, the study lacked a control group receiving a type of intervention other than the experimental protocol. Another limitation was the short duration of follow-up.CONCLUSIONS:
This study suggests that behavioral interventions could be effective in treating atopic dermatitis by reducing eczema and scratching severity. Additionally, habit-reversal behavioral therapy may be more effective for treating atopic dermatitis.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Ensaios Clínicos Controlados Aleatórios como Assunto
/
Dermatite Atópica
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article