Efficacy and safety of radiofrequency ablation versus surgical sympathectomy in palmar hyperhidrosis.
Sci Rep
; 14(1): 7620, 2024 04 01.
Article
em En
| MEDLINE
| ID: mdl-38556580
ABSTRACT
Radiofrequency ablation (RFA) comparative efficacy of treatments using video-assisted thoracoscopic sympathectomy (VATS) in the long term remains uncertain in patients with palmar hyperhidrosis (PHH). This study aimed to compare the efficacy and safety of RFA and VATS in patients with PHH. We recruited patients aged ≥ 14 years with diagnosed PHH from 14 centres in China. The treatment options of RFA or VATS were assigned to two cohort in patients with PHH. The primary outcome was the efficacy at 1-year. A total of 807 patients were enrolled. After propensity score matching, the rate of complete remission was lower in RFA group than VATS group (95% CI 0.21-0.57; p < 0.001). However, the rates of palmar dryness (95% CI 0.38-0.92; p = 0.020), postoperative pain (95% CI 0.13-0.33; p < 0.001), and surgery-related complications (95% CI 0.19-0.85; p = 0.020) were lower in RFA group than in VATS group, but skin temperature rise was more common in RFA group (95% CI 1.84-3.58; p < 0.001). RFA had a lower success rate than VATS for the complete remission of PHH. However, the symptom burden and cost are lower in patients undergoing RFA compared to those undergoing VATS.Trial Registration ChiCTR2000039576, URL http//www.chictr.org.cn/index.aspx .
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Ablação por Radiofrequência
/
Hiperidrose
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article