Poxvirus A51R: A microtubule maestro and virulence virtuoso.

McGillivary, Rebecca M; Luxton, G W Gant

McGillivary, Rebecca M; Luxton, G W Gant.

Afiliação

McGillivary RM; Department of Molecular and Cellular Biology, University of California, Davis, Davis, CA 95616, USA.
Luxton GWG; Department of Molecular and Cellular Biology, University of California, Davis, Davis, CA 95616, USA. Electronic address: ggluxton@ucdavis.edu.

Cell Rep ; 43(4): 114050, 2024 Apr 23.

Article em En | MEDLINE | ID: mdl-38564336

ABSTRACT

ABSTRACT

Seo et al.1 shed light on virus-host interactions as they reveal how poxvirus A51R stabilizes microtubules in infected cells, which impacts vaccinia virus virulence in mice by potentially inhibiting reactive-oxygen-species-dependent antiviral responses in macrophages.

Assuntos

Interações Hospedeiro-Parasita; Microtúbulos; Vaccinia virus; Proteínas Virais; Vaccinia virus/patogenicidade; Vaccinia virus/fisiologia; Virulência; Microtúbulos/metabolismo; Proteínas Virais/metabolismo; Humanos; Animais; Camundongos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vaccinia virus / Proteínas Virais / Interações Hospedeiro-Parasita / Microtúbulos Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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