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Pathophysiology of Eosinophilic Esophagitis.
Kennedy, Kanak V; Muir, Amanda B; Ruffner, Melanie A.
Afiliação
  • Kennedy KV; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Children's Hospital of Philadelphia, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
  • Muir AB; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Abramson Research Center 902E, 3615 Civic Center Boulevard, Philadelphia, PA 19104, USA. Electronic address: MUIRA@chop.edu.
  • Ruffner MA; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Abramson Research Center 902E, 3615 Civic Center Boulevard, Philadelphia, PA 19104, USA; Division of Pediatric Allergy and Immunology, Department of Pediatrics, The Children's Hospital of Philadelphia.
Immunol Allergy Clin North Am ; 44(2): 119-128, 2024 May.
Article em En | MEDLINE | ID: mdl-38575212
ABSTRACT
Eosinophilic esophagitis (EoE) is a chronic, progressive immune-mediated disease associated with antigen-driven type 2 inflammation and symptoms of esophageal dysfunction. Research over the last 2 decades has dramatically furthered our understanding of the complex interplay between genetics, environmental exposures, and cellular and molecular interactions involved in EoE. This review provides an overview of our current understanding of EoE pathogenesis.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esofagite Eosinofílica Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esofagite Eosinofílica Idioma: En Ano de publicação: 2024 Tipo de documento: Article