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Total Synthesis of Quebrachamine and Kopsiyunnanine D.
Liu, Hui; Yuan, Wei; Ran, Meng-Yan; Wei, Gang; Zhao, Yi; Liao, Zhi-Qiang; Liang, Hong; Chen, Zhen-Feng; Wang, Fang-Xin.
Afiliação
  • Liu H; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources/Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China) & Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical
  • Yuan W; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources/Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China) & Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical
  • Ran MY; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources/Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China) & Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical
  • Wei G; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources/Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China) & Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical
  • Zhao Y; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources/Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China) & Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical
  • Liao ZQ; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources/Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China) & Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical
  • Liang H; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources/Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China) & Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical
  • Chen ZF; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources/Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China) & Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical
  • Wang FX; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources/Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China) & Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical
J Org Chem ; 89(8): 5905-5910, 2024 Apr 19.
Article em En | MEDLINE | ID: mdl-38579179
ABSTRACT
The total syntheses of (±)-quebrachamine and (±)-kopsiyunnanine D are reported. Key transformations include an intermolecular Horner-Wadsworth-Emmons olefination to merge the two fragments convergently and an intramolecular Mitsunobu reaction to introduce the synthetically challenging nine-membered azonane ring efficiently.

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article