Crystal structure of (<i>S</i>)-5-(3-acetyl-5-chloro-2-ethoxy-6-fluorophenyl)-2-oxazolidinone.

Li, Victor; Yap, Glenn P A; Ni, Chaoying

Crystal structure of (S)-5-(3-acetyl-5-chloro-2-ethoxy-6-fluorophenyl)-2-oxazolidinone.

Li, Victor; Yap, Glenn P A; Ni, Chaoying.

Afiliação

Li V; W. M. Keck Center for Advanced Microscopy and Microanalysis, University of Delaware, Newark, DE 19716, USA.
Yap GPA; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716, USA.
Ni C; Department of Materials Science and Engineering, University of Delaware, Newark, DE 19716, USA.

Acta Crystallogr E Crystallogr Commun ; 80(Pt 4): 375-377, 2024 Mar 01.

Article em En | MEDLINE | ID: mdl-38584728

ABSTRACT

ABSTRACT

The structure of (S)-5-(3-acetyl-5-chloro-2-ethoxy-6-fluorophenyl)-2-oxazolidinone, C13H13ClFNO4, at 100âK has monoclinic (P21) symmetry. The compound has a polymeric structure propagated by a screw axis parallel to the b axis with N-Hâ¯O hydrogen bonding. It is of inter-est with respect to efforts in the synthesis of a candidate anti-cancer drug, parsaclisib.

Palavras-chave

anti-cancer; crystal structure; drug; kinase inhibitor; oxazolidinone; parsaclib; pharmaceutical

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links