Minimum information and guidelines for reporting a multiplexed assay of variant effect.
Genome Biol
; 25(1): 100, 2024 04 19.
Article
em En
| MEDLINE
| ID: mdl-38641812
ABSTRACT
Multiplexed assays of variant effect (MAVEs) have emerged as a powerful approach for interrogating thousands of genetic variants in a single experiment. The flexibility and widespread adoption of these techniques across diverse disciplines have led to a heterogeneous mix of data formats and descriptions, which complicates the downstream use of the resulting datasets. To address these issues and promote reproducibility and reuse of MAVE data, we define a set of minimum information standards for MAVE data and metadata and outline a controlled vocabulary aligned with established biomedical ontologies for describing these experimental designs.
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MEDLINE
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Projetos de Pesquisa
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Idioma:
En
Ano de publicação:
2024
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Article