The clinical and immunological features of alopecia areata following SARS-CoV-2 infection or COVID-19 vaccines.
Expert Opin Ther Targets
; 28(4): 273-282, 2024 Apr.
Article
em En
| MEDLINE
| ID: mdl-38646688
ABSTRACT
INTRODUCTION:
Alopecia areata (AA) is an autoimmune disease induced by viral infection or vaccination. With the increased incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the incidence of AA has also increased. Recently the incidence was found to be 7.8% from a previously reported rate of 2.1%. The physical and psychological damage caused by AA could seriously affect patients' lives, while AA is a challenging dermatological disease owing to its complex pathogenesis. AREAS COVERED This paper presents a comprehensive review of the prevalence, pathogenesis and potential therapeutic targets for AA after infection with SARS-CoV-2 or SARS-CoV-2 vaccine. EXPERT OPINION The treatment of AA remains challenging because of the complexity of its pathogenesis. For patients with AA after SARS-CoV-2 infection or vaccination, the use of sex hormones and alternative regenerative therapies may be actively considered in addition to conventional treatments. For preexisting disease, therapeutic agents should be adjusted to the patient's specific condition.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Alopecia em Áreas
/
Vacinas contra COVID-19
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COVID-19
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article