Testing for t(3;8) in MYC/BCL6-rearranged large B-cell lymphoma identifies a high-risk subgroup with inferior survival.
Blood
; 144(1): 113-117, 2024 Jul 04.
Article
em En
| MEDLINE
| ID: mdl-38648564
ABSTRACT
ABSTRACT A reciprocal t(3;8) BCL6MYC fusion is common in large B-cell lymphoma (LBCL) with MYC and BCL6 disruption. These pseudo-double-hit cases are not adverse, whereas t(3;8)-MYC/BCL6 lymphoma has an inferior prognosis relative to other MYC-rearranged LBCL.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Translocação Genética
/
Proteínas Proto-Oncogênicas c-myc
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Linfoma Difuso de Grandes Células B
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Proteínas Proto-Oncogênicas c-bcl-6
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article