A morphological mimic: An NTRK3-rearranged spindle cell neoplasm presenting as a groin mass.
J Cutan Pathol
; 51(8): 572-575, 2024 Aug.
Article
em En
| MEDLINE
| ID: mdl-38661100
ABSTRACT
Neurotrophic receptor tyrosine kinase (NTRK)-rearranged spindle cell neoplasms are a recently described group of soft tissue tumors. They commonly present as a painless mass on the extremities of children and young adults. They are characterized microscopically by a heterogeneous spectrum of infiltrative spindle cell proliferations, which can morphologically mimic several other spindle cell neoplasms. Their identification is vital, as they may be amenable to treatment with tyrosine kinase-targeted therapy. This case report describes a rare NTRK3-rearranged spindle cell neoplasm in the groin of a 29-year-old female and provides further clinical and morphological features of this entity.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias de Tecidos Moles
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Receptor trkC
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Virilha
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article