Your browser doesn't support javascript.
loading
Prion forensics: a multidisciplinary approach to investigate CWD at an illegal deer carcass disposal site.
Schwabenlander, Marc D; Bartz, Jason C; Carstensen, Michelle; Fameli, Alberto; Glaser, Linda; Larsen, Roxanne J; Li, Manci; Shoemaker, Rachel L; Rowden, Gage; Stone, Suzanne; Walter, W David; Wolf, Tiffany M; Larsen, Peter A.
Afiliação
  • Schwabenlander MD; Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
  • Bartz JC; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
  • Carstensen M; Minnesota Center for Prion Research and Outreach, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
  • Fameli A; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
  • Glaser L; Department of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, NE, USA.
  • Larsen RJ; Minnesota Department of Natural Resources, Wildlife Health Program, Forest Lake, MN, USA.
  • Li M; Pennsylvania Cooperative Fish & Wildlife Research Unit, The Pennsylvania State University, University Park, PA, USA.
  • Shoemaker RL; Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
  • Rowden G; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
  • Stone S; Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
  • Walter WD; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
  • Wolf TM; Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
  • Larsen PA; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
Prion ; 18(1): 72-86, 2024 Dec.
Article em En | MEDLINE | ID: mdl-38676289
ABSTRACT
Infectious prions are resistant to degradation and remain infectious in the environment for several years. Chronic wasting disease (CWD) has been detected in cervids inhabiting North America, the Nordic countries, and South Korea. CWD-prion spread is partially attributed to carcass transport and disposal. We employed a forensic approach to investigate an illegal carcass dump site connected with a CWD-positive herd. We integrated anatomic, genetic, and prion amplification methods to discover CWD-positive remains from six white-tailed deer (Odocoileus virginianus) and, using microsatellite markers, confirmed a portion originated from the CWD-infected herd. This approach provides a foundation for future studies of carcass prion transmission risk.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Príons / Cervos / Doença de Emaciação Crônica Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Príons / Cervos / Doença de Emaciação Crônica Idioma: En Ano de publicação: 2024 Tipo de documento: Article