Subacute sclerosing panencephalitis presenting as severe depression in an adult.
BMJ Case Rep
; 17(5)2024 May 02.
Article
em En
| MEDLINE
| ID: mdl-38697683
ABSTRACT
Subacute sclerosing panencephalitis (SSPE) is a fatal disorder that occurs as a rare complication of childhood measles. Symptoms typically manifest between the ages of 5 and 15. While the incidence of SSPE is declining globally, it is still prevalent in regions where measles remains common and vaccination rates are low due to poverty and lack of health education. Diagnosing SSPE can be challenging, particularly when patients exhibit unusual symptoms. A thorough clinical evaluation, including vaccination history, physical examination, electroencephalogram (EEG) and Cerebrospinal fluid (CSF) analysis, can help in making a diagnosis. We present the case of a young woman in her early 20s who initially experienced depressive symptoms, followed by myoclonus, dementia and visual impairment. The patient was ultimately diagnosed with SSPE based on characteristic EEG findings, neuroimaging results, CSF analysis and elevated serum measles antibody levels.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Panencefalite Esclerosante Subaguda
/
Eletroencefalografia
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article