[Multi-omics prediction of lymph node metastasis status in breast cancer].
Zhonghua Zhong Liu Za Zhi
; 46(5): 391-398, 2024 May 23.
Article
em Zh
| MEDLINE
| ID: mdl-38742352
ABSTRACT
Lymph node metastasis status stands as a pivotal prognostic indicator in forecasting the outlook for breast cancer patients. Consequently, precise evaluation of this status holds paramount importance in the staging, treatment, and prognosis of breast cancer. The utilization of radiomics, genomics, proteomics, transcriptomics, and histopathology methodologies has notably enhanced the precision of lymph node metastasis status prediction in breast cancer. This review provides an overview of recent advancements in omics-based lymph node metastasis prediction for breast cancer, elucidating the significance of various omics prediction models and integrated multi-omics models in this predictive endeavor. The overarching goal is to augment the accuracy of preoperative lymph node metastasis status prediction in breast cancer, thereby aiding clinicians in the selection of efficacious personalized treatment strategies, while concurrently averting undertreatment of patients with a heightened risk of metastasis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Mama
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Genômica
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Proteômica
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Metástase Linfática
Idioma:
Zh
Ano de publicação:
2024
Tipo de documento:
Article