Prevalence of the cagA Virulence Factor Varies by Race Among Helicobacter pylori -Infected Patients Undergoing Upper Endoscopy.
Clin Transl Gastroenterol
; 15(6): e1, 2024 Jun 01.
Article
em En
| MEDLINE
| ID: mdl-38742743
ABSTRACT
INTRODUCTION:
We designed a race-conscious study to assess the presence of Helicobacter pylori v irulence factor cagA in a retrospective cohort of patients with active H. pylori infection.METHODS:
We compared cagA status by race in gastric tissue samples from 473 patients diagnosed with active H. pylori infection from 2015 to 2019.RESULTS:
H. pylori + Black patients were 2 times more likely to be cagA + than H. pylori + White patients (82% vs 36%, P < .0001).DISCUSSION:
Presence of cagA is common among endoscopy patients with active H. pylori infection; appropriate testing and treatment of H. pylori can both reduce gastric cancer risk and address health disparities.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Proteínas de Bactérias
/
Helicobacter pylori
/
Infecções por Helicobacter
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Fatores de Virulência
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Antígenos de Bactérias
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article