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Sarcopenia: A dive into metabolism to promote a multimodal, preventive, and regenerative approach.
Boccardi, Virginia.
Afiliação
  • Boccardi V; Division of Gerontology and Geriatrics. Department of Medicine and Surgery, University of Perugia, Perugia, Italy. Electronic address: virginia.boccardi@unipg.it.
Mech Ageing Dev ; 219: 111941, 2024 Jun.
Article em En | MEDLINE | ID: mdl-38750969
ABSTRACT
Sarcopenia, the age-related loss of skeletal muscle mass and function, poses a significant challenge in the field of geriatrics and gerontology, impacting the health and independence of older adults. Understanding and addressing sarcopenia is crucial for optimizing clinical outcomes and enhancing the quality of life along with aging. By synthesizing current research findings and theoretical frameworks, this review elucidates the multifaceted mechanisms underlying sarcopenia, mainly focusing on energy balance and metabolic processes. Furthermore, the manuscript explores the implications of sarcopenia on overall health outcomes, functional decline, and quality of life in older individuals. The study concludes with a perspective on the role of preventive and regenerative medicine in sarcopenia, where the two main lifestyle pillars (exercise and diet) represent key factors.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcopenia Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcopenia Idioma: En Ano de publicação: 2024 Tipo de documento: Article