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Primary epithelioid inflammatory myofibroblastic sarcoma of the brain with EML4::ALK fusion mimicking intra-axial glioma: a case report and brief literature review.
Kim, Eric Eunshik; Park, Chul-Kee; Kang, Koung Mi; Kwak, Yoonjin; Park, Sung-Hye; Won, Jae-Kyung.
Afiliação
  • Kim EE; Departments of Pathology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
  • Park CK; Departments of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
  • Kang KM; Departments of Radiology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
  • Kwak Y; Departments of Pathology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
  • Park SH; Departments of Pathology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
  • Won JK; Departments of Pathology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
J Pathol Transl Med ; 58(3): 141-145, 2024 May.
Article em En | MEDLINE | ID: mdl-38766740
ABSTRACT
An aggressive subtype of inflammatory myofibroblastic tumor, epithelioid inflammatory myofibroblastic sarcoma occurs primarily inside the abdominal cavity, followed by a pulmonary localization. Most harbor anaplastic lymphoma kinase (ALK) gene rearrangements, with RANBP2 and RRBP1 among the well-documented fusion partners. We report the second case of primary epithelioid inflammatory myofibroblastic sarcoma of the brain, with a well-known EML4ALK fusion. The case is notable for its intra-axial presentation that clinico-radiologically mimicked glioma.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article