Evaluation of choroid vascular layer thickness in wet age-related macular degeneration using artificial intelligence.
Photodiagnosis Photodyn Ther
; 47: 104218, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38777310
ABSTRACT
PURPOSE:
To facilitate the assessment of choroid vascular layer thickness in patients with wet age-related macular degeneration (AMD) using artificial intelligence (AI).METHODS:
We included 194 patients with wet AMD and 225 healthy participants. Choroid images were obtained using swept-source optical coherence tomography. The average Sattler layer-choriocapillaris complex thickness (SLCCT), Haller layer thickness (HLT), and choroidal thickness (CT) were auto-measured at 7 regions centered around the foveola using AI and subsequently compared between the 2 groups.RESULTS:
The SLCCT was lower in the AMD group than in the control group (P < 0.05). The HLT was significantly higher in the AMD group than in the control group at the Tparafovea and T-perifovea in the total population (P < 0.05) and in the ≤70-year subgroup (P < 0.05). The CT was higher in the AMD group than in the control group, particularly at the N-perifovea, T-perifovea, and T-parafovea in the ≤70-year subgroup; Interestingly, it was lower in the AMD group than in the control group at the Nparafovea, N-fovea, foveola, and T-fovea in the >70-year subgroup (P < 0.05).CONCLUSION:
This novel AI-based auto-measurement was more accurate, efficient, and detailed than manual measurements. SLCCT thinning was observed in wet AMD; however, CT changes depended on the interaction between HLT compensatory thickening and SLCCT thinning.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Inteligência Artificial
/
Corioide
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Tomografia de Coerência Óptica
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Degeneração Macular Exsudativa
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article