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Diet xylo-oligosaccharide supplementation improves growth performance, immune function, and intestinal health of broilers.
Rao, Zhiyong; Li, Yue; Yang, Xiaopeng; Guo, Yongpeng; Zhang, Wei; Wang, Zhixiang.
Afiliação
  • Rao Z; School of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450002, China.
  • Li Y; School of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450002, China.
  • Yang X; School of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450002, China.
  • Guo Y; School of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450002, China.
  • Zhang W; School of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450002, China.
  • Wang Z; School of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450002, China.
Anim Nutr ; 17: 165-176, 2024 Jun.
Article em En | MEDLINE | ID: mdl-38779325
ABSTRACT
The effects of xylo-oligosaccharides (XOS) on broiler growth performance, immune function, and intestinal health were investigated. A total of 540 one-d-old Arbor Acres Plus broilers were randomly divided into 5 groups with 6 replicates per group and 18 chickens per replicate. Broilers in the control (CON) group received a corn-soybean meal based basal diet, those in the antibiotics (ANT) group received the basal diet plus 500 mg/kg oxytetracycline, and those in XOS groups received the basal diet plus 150, 300, or 450 mg/kg XOS. Compared with CON, the body weight at 42 d and average daily gain from 1 to 42 d were significantly increased in the 150, 450 mg/kg XOS-added and ANT groups (P = 0.018), and the relative expression of claudin-1 and ZO-1 mRNA in the ileum was significantly higher in the 300 and 450 mg/kg XOS-added groups (P < 0.001). The feed conversion ratios (P < 0.001) and abdominal fat rates (P = 0.012) of broilers from 1 to 42 d of age were significantly lower in all XOS-added groups than in the control group. Splenic index (P = 0.036) and bursa of Fabricius index (P = 0.009) were significantly better in the ANT group and each XOS-added group than in the control group. Compared to CON and ANT, serum IgA (P = 0.007) and IgG (P = 0.002) levels were significantly higher in the 300 mg/kg XOS-added group, and the relative abundance of short-chain fatty acid-producing genera (Alistipes) was also significantly higher (P < 0.001). Meanwhile, ileal villus height (P < 0.001) and ratio of villus height to crypt depth (VC) (P = 0.001) were significantly increased in XOS-added broilers. In analysis of relationships between cecal microbes and the physical barrier of the gut, [Ruminococcus]_torques_group was positively correlated with mRNA expression of ileal ZO-1 and claudin-1 (P < 0.05), and Bacteroides was positively correlated with increased ileal villus height and VC (P < 0.05). Overall, XOS addition to broiler diets improved growth performance, promoted intestinal health by enhancing intestinal barrier function and regulating cecal microbiota diversity, and had positive effects on immunity.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article