Catalytic Epoxidation of Carbonyl Compounds via Carbonyl Ylides: from Racemic to Enantioselective.
Chemistry
; 30(41): e202401389, 2024 Jul 19.
Article
em En
| MEDLINE
| ID: mdl-38779789
ABSTRACT
Transition metal-catalyzed epoxidation of carbonyl compounds through carbonyl ylides represents a highly effective method for synthesizing a diverse range of valuable epoxides. This review offers an in-depth overview of the latest developments in inter- and intramolecular epoxidation reactions involving metal carbenes and carbonyl compounds, encompassing both racemic to enantioselective transformations. These catalytic epoxidations are reviewed by highlighting their product selectivity, diversity and applicability, and the related mechanistic rationale is showcased where possible.
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MEDLINE
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article