Satiety controls behavior in Hydra through an interplay of pre-enteric and central nervous system-like neuron populations.
Cell Rep
; 43(6): 114210, 2024 Jun 25.
Article
em En
| MEDLINE
| ID: mdl-38787723
ABSTRACT
Hunger and satiety can have an influence on decision-making, sensory processing, and motor behavior by altering the internal state of the brain. This process necessitates the integration of peripheral sensory stimuli into the central nervous system. Here, we show how animals without a central nervous system such as the cnidarian Hydra measure and integrate satiety into neuronal circuits and which specific neuronal populations are involved. We demonstrate that this simple nervous system, previously referred to as diffuse, has an endodermal subpopulation (N4) similar to the enteric nervous system (feeding-associated behavior) and an ectodermal population (N3) that performs central nervous system-like functions (physiology/motor). This view of a supposedly simple nervous system could open an important window into the origin of more complex nervous systems.
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Base de dados:
MEDLINE
Assunto principal:
Sistema Nervoso Central
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Sistema Nervoso Entérico
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Hydra
/
Neurônios
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article