Neural deception: Breast cancer co-opts neuronal mechanisms to evade the immune system.
Cancer Cell
; 42(6): 936-938, 2024 Jun 10.
Article
em En
| MEDLINE
| ID: mdl-38821062
ABSTRACT
Cellular mechanisms mediating immunotherapy resistances are incompletely understood. In this issue, Li et al. reveal how breast cancer hijacks neuronal mechanisms of neuroprotection to shield itself from the immune system. Secretion of N-acetylaspartate impairs immune synapse formation in both neuroinflammation and breast cancer models, paving the way for novel therapeutic approaches.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Mama
/
Neurônios
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article