Molecular Pathology of Urothelial Carcinoma.
Clin Lab Med
; 44(2): 181-198, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38821640
ABSTRACT
Urothelial carcinoma is characterized by the presence of a wide spectrum of histopathologic features and molecular alterations that contribute to its morphologic and genomic heterogeneity. It typically harbors high rates of somatic mutations with considerable genomic and transcriptional complexity and heterogeneity that is reflective of its varied histomorphologic and clinical features. This review provides an update on the recent advances in the molecular characterization and novel molecular taxonomy of urothelial carcinoma and variant histologies.
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Base de dados:
MEDLINE
Assunto principal:
Carcinoma de Células de Transição
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article