Five New Furostanol Glycosides from the Fruits of Tribulus terrestris with NO Production Inhibitory Activity.
Chem Biodivers
; : e202401273, 2024 Jun 03.
Article
em En
| MEDLINE
| ID: mdl-38828879
ABSTRACT
Eight furostanol glycosides including five undescribed compounds, named tribufurostanosides A-E (1-5), and three known ones (6-8) were isolated from the fruits of Tribulus terrestris L. Their chemical structures were determined by the IR, HR-ESI-MS, 1D-, and 2D-NMR spectra. Furostanols 1-8 significantly inhibited nitric oxide production in LPS activated RAW 264.7â
cells with IC50 values ranging from 14.2 to 64.7â
µM, compared to that of the positive control compound, dexamethazone (IC50 13.6â
µM).
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Base de dados:
MEDLINE
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En
Ano de publicação:
2024
Tipo de documento:
Article