Anticancer nano-prodrugs with drug release triggered by intracellular dissolution and hydrogen peroxide response.
Chem Commun (Camb)
; 60(50): 6427-6430, 2024 Jun 18.
Article
em En
| MEDLINE
| ID: mdl-38829169
ABSTRACT
We developed prodrug nanoparticles that release drugs through intracellular dissolution and a cancer-specific hydrogen peroxide response. To reveal the unclear mechanism regarding drug release from nanoparticles by reacting with hydrogen peroxide in cancer cells, this study demonstrates the in vitro evaluation of drug release kinetics under conditions simulated in cancer cells.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pró-Fármacos
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Nanopartículas
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Liberação Controlada de Fármacos
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Peróxido de Hidrogênio
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Antineoplásicos
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article