Your browser doesn't support javascript.
loading
A Carbamoyl Oxime-Based Highly Specific Fluorescent Chemodosimeter for Monitoring Labile Fe2+ in Food and Living Organisms.
Yan, Tingyi; Wang, Xin; Liu, Caiyun; Cai, Xinyu; Wang, Yao; Liu, Xueting; Rong, Xiaodi; Wang, Kun; Li, Wenzhai; Sheng, Wenlong; Zhu, Baocun.
Afiliação
  • Yan T; School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China.
  • Wang X; School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China.
  • Liu C; School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China.
  • Cai X; School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China.
  • Wang Y; School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China.
  • Liu X; School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China.
  • Rong X; School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China.
  • Wang K; School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China.
  • Li W; Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
  • Sheng W; Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
  • Zhu B; School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China.
J Agric Food Chem ; 72(23): 13341-13347, 2024 Jun 12.
Article em En | MEDLINE | ID: mdl-38830118
ABSTRACT
Iron is an essential element in the composition of living organisms and plays a crucial role in a wide range of biological activities. The human body primarily obtains essential iron through the consumption of food. Therefore, it is vital for the health of human body to maintain iron homeostasis. The reducing character of the cellular microenvironment enables Fe2+ to occupy a dominant position within the cell. Hence, there is an urgent need for a simple and sensitive tool that can detect a large amount of Fe2+ in organisms. In this work, a highly specific fluorescent chemodosimeter NPCO ("NP" represents the naphthalimide fluorophore, and "CO" represents the carbamoyl oxime structure) for the detection of Fe2+ with excellent sensitivity (LOD = 82 nM) was constructed by incorporating a novel carbamoyl oxime structure as the recognition group. NPCO can be effectively employed for the detection of Fe2+ in food samples, living cells, and zebrafish. Furthermore, by using soybean sprouts as a model plant, the application of NPCO was expanded to detect Fe2+ in plants. Therefore, NPCO could be used as an excellent assay tool for detecting Fe2+ in organisms and is expected to be an important aid in exploring the mechanism of iron regulation.
Assuntos
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oximas / Peixe-Zebra / Corantes Fluorescentes / Ferro Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oximas / Peixe-Zebra / Corantes Fluorescentes / Ferro Idioma: En Ano de publicação: 2024 Tipo de documento: Article