Treatment of Chronic Pouchitis With JAK Inhibitors: Results from A Large Multicenter Database.

Alsakarneh, Saqr; Desai, Aakash; Kochhar, Gursimran S; Farraye, Francis A; Hashash, Jana G

Alsakarneh, Saqr; Desai, Aakash; Kochhar, Gursimran S; Farraye, Francis A; Hashash, Jana G.

Afiliação

Alsakarneh S; Department of Medicine, University of Missouri-Kansas City, Kansas City, MO, USA.
Desai A; Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Jacksonville, FL, USA.
Kochhar GS; Division of Gastroenterology, Hepatology and Nutrition, Allegheny Health Network, Pittsburgh, PA, USA.
Farraye FA; Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Jacksonville, FL, USA.
Hashash JG; Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Jacksonville, FL, USA.

Inflamm Bowel Dis ; 2024 Jun 03.

Article em En | MEDLINE | ID: mdl-38830629

This retrospective study assessed the use of Janus kinase inhibitors in treating chronic pouchitis. While showing relative safety, Janus kinase inhibitors demonstrated effectiveness in <50% of cases, cautioning against their use as first-line agents. Larger randomized trials are recommended for further investigation.

Palavras-chave

JAK inhibitors; Janus kinase inhibitors; chronic; pouchitis; ulcerative colitis

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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