Extracellular fluid excess linked to reduced choroidal vascularity index in patients with chronic kidney disease.
Sci Rep
; 14(1): 12769, 2024 06 04.
Article
em En
| MEDLINE
| ID: mdl-38834727
ABSTRACT
Extracellular fluid (ECF) excess is common in patients with chronic kidney disease (CKD). This study (involving 284 patients with CKD) explored the association between choroidal vascularity index (CVI) and ECF excess. We categorised patients into three groups based on extracellular water/total body water normal, mildly overhydrated, and severely overhydrated. The more severe ECF status was associated with a lower CVI after adjustment (B = - 0.902, p = 0.001). In non-diabetic patients, both vascular luminal (LA, p < 0.001) and stromal areas (SA, p = 0.003) were significantly reduced in patients with severe ECF excess compared to others, whereas diabetic patients showed no significant differences in LA (p = 0.96) and SA (p = 0.86) based on ECF excess status. These findings suggest that ECF status may influence CVI in patients with CKD, underscoring the need for further research to clarify its direct impact on choroidal changes.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Corioide
/
Líquido Extracelular
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Insuficiência Renal Crônica
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article