Legionella effectors SidC/SdcA ubiquitinate multiple small GTPases and SNARE proteins to promote phagosomal maturation.

Ma, Kelong; Shu, Rundong; Liu, Hongtao; Ge, Jinli; Liu, Jiayang; Lu, Qian; Fu, Jiaqi; Liu, Xiaoyun; Qiu, Jiazhang

Ma, Kelong; Shu, Rundong; Liu, Hongtao; Ge, Jinli; Liu, Jiayang; Lu, Qian; Fu, Jiaqi; Liu, Xiaoyun; Qiu, Jiazhang.

Afiliação

Ma K; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Center for Pathogen Biology and Infectious Diseases, The First Hospital of Jilin University, C
Shu R; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Center for Pathogen Biology and Infectious Diseases, The First Hospital of Jilin University, C
Liu H; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Center for Pathogen Biology and Infectious Diseases, The First Hospital of Jilin University, C
Ge J; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Center for Pathogen Biology and Infectious Diseases, The First Hospital of Jilin University, C
Liu J; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Center for Pathogen Biology and Infectious Diseases, The First Hospital of Jilin University, C
Lu Q; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Center for Pathogen Biology and Infectious Diseases, The First Hospital of Jilin University, C
Fu J; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, College of Veterinary Medicine, Jilin University, Center for Pathogen Biology and Infectious Diseases, The First Hospital of Jilin University, C
Liu X; Department of Microbiology and Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Qiu J; NHC Key Laboratory of Medical Immunology, Peking University, Beijing, China.

Cell Mol Life Sci ; 81(1): 249, 2024 Jun 05.

Article em En | MEDLINE | ID: mdl-38836877

Assuntos

Legionella pneumophila; Fagossomos; Proteínas SNARE; Ubiquitinação; Proteínas rab de Ligação ao GTP; Legionella pneumophila/metabolismo; Humanos; Fagossomos/metabolismo; Fagossomos/microbiologia; Proteínas SNARE/metabolismo; Proteínas rab de Ligação ao GTP/metabolismo; Proteínas de Bactérias/metabolismo; Proteínas de Bactérias/genética; Animais; Proteínas Qa-SNARE/metabolismo; Ubiquitina-Proteína Ligases/metabolismo; Ubiquitina-Proteína Ligases/genética; Vacúolos/metabolismo; Vacúolos/microbiologia; Células HEK293; Camundongos; proteínas de unión al GTP Rab7/metabolismo; Proteínas Monoméricas de Ligação ao GTP/metabolismo; Retículo Endoplasmático/metabolismo

Palavras-chave

Effector proteins; Legionella pneumophila; RILP; Rab small GTPase; SNARE proteins; Ubiquitination

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fagossomos / Legionella pneumophila / Proteínas rab de Ligação ao GTP / Proteínas SNARE / Ubiquitinação Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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