Interrelationship of Sarcopenia and Cardiovascular Diseases: A Review of Potential Mechanisms and Management.
J ASEAN Fed Endocr Soc
; 39(1): 69-78, 2024.
Article
em En
| MEDLINE
| ID: mdl-38863922
ABSTRACT
Sarcopenia refers to an age-related reduction of lean body mass. It showed a reciprocal relationship with cardiovascular diseases. Thus, it is imperative to explore pathophysiological mechanisms explaining the relationship between sarcopenia and cardiovascular diseases, along with the clinical assessment, and associated management. In this review, we discuss how processes such as inflammation, oxidative stress, endothelial dysfunction, neural and hormonal modifications, as well as other metabolic disturbances influence sarcopenia as well as its association with cardiovascular diseases. Moreover, this review provides an overview of both non-pharmacological and pharmacological management for patients with sarcopenia and cardiovascular diseases, with a focus on the potential role of cardiovascular drugs to mitigate sarcopenia.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Cardiovasculares
/
Sarcopenia
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article