The triglyceride glucose index was nonlinearly associated with all-cause mortality in diabetic patients.
Nutr Metab Cardiovasc Dis
; 34(8): 2012-2015, 2024 Aug.
Article
em En
| MEDLINE
| ID: mdl-38866610
ABSTRACT
BACKGROUND AND AIM:
The TyG index has been linked with cardiometabolic diseases. Our study aimed to investigate the specific relationship between the triglyceride and glucose index (TyG) and both all-cause and cardiovascular mortality in diabetic patients. METHODS ANDRESULTS:
We enrolled 3120 participants with diabetes from the National Health and Nutrition Examination Survey. The TyG index was calculated using the formula ln [fasting triglycerides (mg/dL) × fasting glucose (mg/dL)/2]. Hazard ratios (HRs) of TyG associated with mortality risk were assessed using Cox proportional hazard regression models. Over a follow-up period of 10.8 thousand person-years, we observed 768 all-cause deaths and 155 cardiovascular deaths. Compared to the reference quartile, the multivariate-adjusted hazard ratios and 95% confidence intervals for all-cause mortality were 1.02 (1.01-1.05; p = 0.008) in the fourth quartile. Dose-response analysis revealed a non-linear association. However, no significant associations were found between the TyG index and cardiovascular mortality.CONCLUSIONS:
The TyG index exhibited a non-linear association with the risk of all-cause mortality in diabetic patients.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Triglicerídeos
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Glicemia
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Biomarcadores
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Inquéritos Nutricionais
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Causas de Morte
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Diabetes Mellitus
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article