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Cavitation is the determining mechanism for the atomization of high-viscosity liquid.
Gui, Zhenzhen; Zeng, Yaohua; Xie, Tang; Chen, Bochuan; Wang, Jialong; Wen, Yuxin; Tan, Tian; Zou, Tao; Zhang, Fan; Zhang, Jianhui.
Afiliação
  • Gui Z; School of Mechanical and Electrical Engineering, Guangzhou University, Guangzhou Higher Education Mega Center, 230 Wai Huan Xi Road, Guangzhou 510006, China.
  • Zeng Y; School of Mechanical and Electrical Engineering, Guangzhou University, Guangzhou Higher Education Mega Center, 230 Wai Huan Xi Road, Guangzhou 510006, China.
  • Xie T; School of Mechanical and Electrical Engineering, Guangzhou University, Guangzhou Higher Education Mega Center, 230 Wai Huan Xi Road, Guangzhou 510006, China.
  • Chen B; School of Mechanical and Electrical Engineering, Guangzhou University, Guangzhou Higher Education Mega Center, 230 Wai Huan Xi Road, Guangzhou 510006, China.
  • Wang J; School of Mechanical and Electrical Engineering, Guangzhou University, Guangzhou Higher Education Mega Center, 230 Wai Huan Xi Road, Guangzhou 510006, China.
  • Wen Y; School of Mechanical and Electrical Engineering, Guangzhou University, Guangzhou Higher Education Mega Center, 230 Wai Huan Xi Road, Guangzhou 510006, China.
  • Tan T; School of Mechanical and Electrical Engineering, Guangzhou University, Guangzhou Higher Education Mega Center, 230 Wai Huan Xi Road, Guangzhou 510006, China.
  • Zou T; School of Mechanical and Electrical Engineering, Guangzhou University, Guangzhou Higher Education Mega Center, 230 Wai Huan Xi Road, Guangzhou 510006, China.
  • Zhang F; Guangdong-Hong Kong-Macao Key Laboratory of Multi-scale Information Fusion and Collaborative Optimization Control of Complex Manufacturing Process, Guangzhou 510006, China.
  • Zhang J; School of Mechanical and Electrical Engineering, Guangzhou University, Guangzhou Higher Education Mega Center, 230 Wai Huan Xi Road, Guangzhou 510006, China.
iScience ; 27(6): 110071, 2024 Jun 21.
Article em En | MEDLINE | ID: mdl-38868199
ABSTRACT
Piezoelectric atomization is becoming mainstream in the field of inhalation therapy due to its significant advantages. With the rapid development of high-viscosity gene therapy drugs, the demand for piezoelectric atomization devices is increasing. However, conventional piezoelectric atomizers with a single-dimensional energy supply are unable to provide the energy required to atomize high-viscosity liquids. To address this problem, our team has designed a flow tube internal cavitation atomizer (FTICA). This study focuses on dissecting the atomization mechanism of FTICA. In contrast to the widely supported capillary wave hypothesis, our study provides evidence in favor of the cavitation hypothesis, proving that cavitation is the key to atomizing high-viscosity liquids with FTICA. In order to prove that the cavitation is the key to atomizing in the structure of FTICA, the performance of atomization is experimented after changing the cavitation conditions by heating and stirring of the liquids.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article