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Severe Mpox Among People With Advanced Human Immunodeficiency Virus Receiving Prolonged Tecovirimat in New York City.
Garcia, Elizabeth A; Foote, Mary M K; McPherson, Tristan D; Lash, Maura K; Bosompem, Amma N; Bouscaren, Alyssa; Chan, Justin; DiLorenzo, Madeline A; Feihel, Dennis; Fowler, Randal C; Gandhi, Vani; Jenny-Avital, Elizabeth R; Kopping, Erik J; Mazo, Dana; McLean, Jacob; Mgbako, Ofole; Sayegh, Mark N; Shaw, Raphael N; Su, Michelle; Meissner, Jeanne Sullivan; Wang, Jade C; Wen, Wendy; Winters, John C; Zeana, Cosmina B; Zucker, Jason; Wong, Marcia.
Afiliação
  • Garcia EA; Division of Disease Control, New York City Department of Health and Mental Hygiene, Queens, New York, USA.
  • Foote MMK; Division of Disease Control, New York City Department of Health and Mental Hygiene, Queens, New York, USA.
  • McPherson TD; Division of Disease Control, New York City Department of Health and Mental Hygiene, Queens, New York, USA.
  • Lash MK; Division of Disease Control, New York City Department of Health and Mental Hygiene, Queens, New York, USA.
  • Bosompem AN; Human Resources Administration, New York City Department of Social Services, New York, New York, USA.
  • Bouscaren A; Department of Homeless Services, New York City Department of Social Services, New York, New York, USA.
  • Chan J; Division of Infectious Diseases and Immunology, New York University Grossman School of Medicine, New York, New York, USA.
  • DiLorenzo MA; Department of Internal Medicine and Infectious Diseases, NYC Health + Hospitals/Bellevue, New York, New York, USA.
  • Feihel D; Division of Infectious Diseases and Immunology, New York University Grossman School of Medicine, New York, New York, USA.
  • Fowler RC; Lenox Hill Hospital Department of Medicine, Northwell Health, New York, New York, USA.
  • Gandhi V; Division of Disease Control, New York City Department of Health and Mental Hygiene, Queens, New York, USA.
  • Jenny-Avital ER; Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
  • Kopping EJ; Division of Infectious Diseases, NYC Health + Hospitals/Jacobi, Bronx, New York, USA.
  • Mazo D; Division of Disease Control, New York City Department of Health and Mental Hygiene, Queens, New York, USA.
  • McLean J; Division of Infectious Diseases and Immunology, New York University Grossman School of Medicine, New York, New York, USA.
  • Mgbako O; Division of Infectious Diseases, New York Presbyterian Hospital, Columbia University, New York, New York, USA.
  • Sayegh MN; Division of Infectious Diseases and Immunology, New York University Grossman School of Medicine, New York, New York, USA.
  • Shaw RN; Department of Internal Medicine and Infectious Diseases, NYC Health + Hospitals/Bellevue, New York, New York, USA.
  • Su M; New York University Langone Institute for Excellence in Health Equity, NYU Langone Health, New York, New York, USA.
  • Meissner JS; Division of Infectious Diseases, NYC Health + Hospitals/Harlem, New York, New York, USA.
  • Wang JC; Division of Infectious Diseases, Columbia University, New York, New York, USA.
  • Wen W; Division of Infectious Diseases, NYC Health + Hospitals/Harlem, New York, New York, USA.
  • Winters JC; Division of Infectious Diseases, Columbia University, New York, New York, USA.
  • Zeana CB; Division of Disease Control, New York City Department of Health and Mental Hygiene, Queens, New York, USA.
  • Zucker J; Division of Disease Control, New York City Department of Health and Mental Hygiene, Queens, New York, USA.
  • Wong M; Division of Disease Control, New York City Department of Health and Mental Hygiene, Queens, New York, USA.
Open Forum Infect Dis ; 11(6): ofae294, 2024 Jun.
Article em En | MEDLINE | ID: mdl-38868307
ABSTRACT
Severe mpox has been observed in people with advanced human immunodeficiency virus (HIV). We describe clinical outcomes of 13 patients with advanced HIV (CD4 <200 cells/µL), severe mpox, and multiorgan involvement. Despite extended tecovirimat courses and additional agents, including vaccinia immune globulin, cidofovir, and brincidofovir, this group experienced prolonged hospitalizations and high mortality.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article