Quantitative SERS sensor for mycotoxins with extraction and identification function.
Food Chem
; 456: 140040, 2024 Oct 30.
Article
em En
| MEDLINE
| ID: mdl-38878539
ABSTRACT
The development of new sensors for on-site food toxin monitoring that combine extraction, analytes distinction and detection is important in resource-limited environments. Surface-enhanced Raman scattering (SERS)-based signal readout features fast response and high sensitivity, making it a powerful method for detecting mycotoxins. In this work, a SERS-based assay for the detection of multiple mycotoxins is presented that combines extraction and subsequent detection, achieving an analytically relevant detection limit (â¼ 1 ng/mL), which is also tested in corn samples. This sensor consists of a magnetic-core and mycotoxin-absorbing polydopamine-shell, with SERS-active Au nanoparticles on the outer surface. The assay can concentrate multiple mycotoxins, which are identified through multiclass partite least squares analysis based on their SERS spectra. We developed a strategy for the analysis of multiple mycotoxins with minimal sample pretreatment, enabling in situ analytical extraction and subsequent detection, displaying the potential to rapidly identify lethal mycotoxin contamination on site.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Análise Espectral Raman
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Contaminação de Alimentos
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Zea mays
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Nanopartículas Metálicas
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Ouro
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Micotoxinas
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article