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Effect of Patient's Symptom Interpretation on In-Hospital Mortality in Acute Coronary Syndrome.
Ninomiya, Ryo; Koeda, Yorihiko; Nasu, Takahito; Ishida, Masaru; Yoshizawa, Reisuke; Ishikawa, Yu; Itoh, Tomonori; Morino, Yoshihiro; Saito, Hidenori; Onodera, Hiroyuki; Nozaki, Tetsuji; Maegawa, Yuko; Nishiyama, Osamu; Ozawa, Mahito; Osaki, Takuya; Nakamura, Akihiro.
Afiliação
  • Ninomiya R; Division of Cardiology, Department of Internal Medicine, Iwate Medical University.
  • Koeda Y; Division of Cardiology, Department of Internal Medicine, Iwate Medical University.
  • Nasu T; Division of Cardiology, Department of Internal Medicine, Iwate Medical University.
  • Ishida M; Division of Cardiology, Department of Internal Medicine, Iwate Medical University.
  • Yoshizawa R; Division of Cardiology, Department of Internal Medicine, Iwate Medical University.
  • Ishikawa Y; Division of Cardiology, Department of Internal Medicine, Iwate Medical University.
  • Itoh T; Division of Cardiology, Department of Internal Medicine, Iwate Medical University.
  • Morino Y; Division of Cardiology, Department of Internal Medicine, Iwate Medical University.
  • Saito H; Department of Cardiology, Iwate Prefectural Chubu Hospital.
  • Onodera H; Department of Cardiology, Iwate Prefectural Iwai Hospital.
  • Nozaki T; Department of Cardiology, Iwate Prefectural Isawa Hospital.
  • Maegawa Y; Department of Cardiology, Iwate Prefectural Miyako Hospital.
  • Nishiyama O; Department of Cardiology, Iwate Prefectural Ninohe Hospital.
  • Ozawa M; Department of Cardiology, Japanese Red Cross Morioka Hospital.
  • Osaki T; Department of Cardiology, Iwate Prefectural Kuji Hospital.
  • Nakamura A; Department of Cardiology, Iwate Prefectural Central Hospital.
Circ J ; 88(8): 1225-1234, 2024 07 25.
Article em En | MEDLINE | ID: mdl-38880608
ABSTRACT

BACKGROUND:

The association between symptom interpretation and prognosis has not been investigated well among patients with acute coronary syndrome (ACS). As such, the present study evaluated the effect of heart disease awareness among patients with ACS on in-hospital mortality. METHODS AND 

RESULTS:

We performed a post hoc analysis of 1,979 consecutive patients with ASC with confirmed symptom interpretation on admission between 2014 and 2018, focusing on patient characteristics, recanalization time, and clinical outcomes. Upon admission, 1,264 patients interpreted their condition as cardiac disease, whereas 715 did not interpret their condition as cardiac disease. Although no significant difference was observed in door-to-balloon time between the 2 groups, onset-to-balloon time was significantly shorter among those who interpreted their condition as cardiac disease (254 vs. 345 min; P<0.001). Moreover, the hazard ratio (HR) for in-hospital mortality was significantly higher among those who did not interpret their condition as cardiac disease based on the Cox regression model adjusted for established risk factors (HR 1.73; 95% confidence interval 1.08-2.76; P=0.022).

CONCLUSIONS:

This study demonstrated that prehospital symptom interpretation was significantly associated with in-hospital clinical outcomes among patients with ACS. Moreover, the observed differences in clinical prognosis were not related to door-to-balloon time, but may be related to onset-to-balloon time.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mortalidade Hospitalar / Síndrome Coronariana Aguda Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mortalidade Hospitalar / Síndrome Coronariana Aguda Idioma: En Ano de publicação: 2024 Tipo de documento: Article