Cardiac Development and Animal Models of Congenital Heart Defects.
Adv Exp Med Biol
; 1441: 77-85, 2024.
Article
em En
| MEDLINE
| ID: mdl-38884705
ABSTRACT
The major events of cardiac development, including early heart formation, chamber morphogenesis and septation, and conduction system and coronary artery development, are briefly reviewed together with a short introduction to the animal species commonly used to study heart development and model congenital heart defects (CHDs).
Palavras-chave
Arterial pole; Atrioventricular canal; Atrioventricular cushionsAtrioventricularcushion; Atrioventricular septal defect; Cardiac conduction system; Cardiac crescent; Cardiac neural crest cells; Cardiac progenitor cells; Chick; Ciona intestinalis; Common arterial trunk; Double outlet right ventricle; Drosophila melanogaster; Endocardial cushions; Endocardium; Epicardium; Heart tube; Leftright axis; Looping; Mouse; N-ethyl-N-nitrosourea; NKX25; Outflow tract; Pharyngeal arch arteries; Pharyngeal mesoderm; Purkinje fibers; Second heart field; Septation; T-box 1; Tetralogy of Fallot; Trabeculae; Venous pole; Xenopus; Zebrafish
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Modelos Animais de Doenças
/
Coração
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Cardiopatias Congênitas
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article