Self-degradable photosensitizer exhibiting bacterial agglutination and membrane insertion toward safe photodynamic ablation.

Zhou, Chengcheng; Li, Yimei; Shen, Yihui; Lv, Ze; Feng, Jianguo; Jiang, Meijuan; Du, Jian; Guan, Weijiang

Zhou, Chengcheng; Li, Yimei; Shen, Yihui; Lv, Ze; Feng, Jianguo; Jiang, Meijuan; Du, Jian; Guan, Weijiang.

Afiliação

Zhou C; School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China. zhoucc@yzu.edu.cn.
Li Y; School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China. zhoucc@yzu.edu.cn.
Shen Y; School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China. zhoucc@yzu.edu.cn.
Lv Z; College of Plant Protection, Yangzhou University, Yangzhou 225009, China.
Feng J; College of Plant Protection, Yangzhou University, Yangzhou 225009, China.
Jiang M; Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China.
Du J; Department of Urology, The First Affiliated Hospital of Shandong First Medical University, No. 16766, Jingshi Road, Jinan 250000, China.
Guan W; State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China. wjguan@mail.buct.edu.cn.

Chem Commun (Camb) ; 60(55): 7053-7056, 2024 Jul 04.

Article em En | MEDLINE | ID: mdl-38899451

ABSTRACT

ABSTRACT

Self-oxidative degradation photosensitizers capable of bacterial agglutination and membrane insertion were fabricated based on a simple co-assembly strategy, for efficiently killing P. aeruginosa and rapidly deactivating their function post-treatment.

Assuntos

Fotoquimioterapia; Fármacos Fotossensibilizantes; Pseudomonas aeruginosa; Fármacos Fotossensibilizantes/química; Fármacos Fotossensibilizantes/farmacologia; Pseudomonas aeruginosa/efeitos dos fármacos; Antibacterianos/química; Antibacterianos/farmacologia; Humanos; Membrana Celular/efeitos dos fármacos; Membrana Celular/química; Membrana Celular/metabolismo; Aglutinação/efeitos dos fármacos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fotoquimioterapia / Pseudomonas aeruginosa / Fármacos Fotossensibilizantes Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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