Strategies for the development of metalloimmunotherapies.
Nat Biomed Eng
; 2024 Jun 24.
Article
em En
| MEDLINE
| ID: mdl-38914800
ABSTRACT
Metal ions play crucial roles in the regulation of immune pathways. In fact, metallodrugs have a long record of accomplishment as effective treatments for a wide range of diseases. Here we argue that the modulation of interactions of metal ions with molecules and cells involved in the immune system forms the basis of a new class of immunotherapies. By examining how metal ions modulate the innate and adaptive immune systems, as well as host-microbiota interactions, we discuss strategies for the development of such metalloimmunotherapies for the treatment of cancer and other immune-related diseases.
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MEDLINE
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article