High Risk of Non-Melanoma Skin Cancer in Actinic Keratosis Patients with Skin of Color: A Nationwide Register-Based Cohort Study.
Dermatology
; : 1-5, 2024 Jun 27.
Article
em En
| MEDLINE
| ID: mdl-38934144
ABSTRACT
INTRODUCTION:
Actinic keratoses (AKs) are rough, scaly patches from UV exposure, increasing the risk of non-melanoma skin cancer (NMSC). This study examines AK incidence in Korea and its role as a risk factor for NMSC.METHODS:
A retrospective nationwide register-based cohort study analyzed 2,917 AK patients and 14,585 controls from 2002 to 2019. Patients diagnosed with AK were followed until NMSC occurrence, death, emigration, or December 2019.RESULTS:
AK incidence reached 44.8 per 100,000 person-years in 2019. The adjusted hazard ratio for NMSC in AK patients was 8.91 (95% confidence interval, 5.72-13.90). Higher NMSC risk was observed in female AK patients, those under 60 years, and those with lower income levels. The 16-year cumulative incidence of NMSC was 4.19% in AK patients versus 0.44% in controls.CONCLUSION:
AK significantly increases the risk of NMSC in Koreans, highlighting the need for tailored surveillance and treatment strategies.
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MEDLINE
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Ano de publicação:
2024
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Article