[Research progress in dual immune regulation of neutrophils in periodontal inflammation].
Zhonghua Kou Qiang Yi Xue Za Zhi
; 59(7): 721-725, 2024 Jul 09.
Article
em Zh
| MEDLINE
| ID: mdl-38949141
ABSTRACT
Periodontitis is a chronic inflammatory condition of the periodontal tissues triggered by bacterial biofilm, leading to manifestations such as gingival bleeding, tooth mobility, and eventual exfoliation. Neutrophils exhibit a dual role throughout the course of periodontitis, both in defense against pathogens and in potentially detrimental effects on periodontal tissues. This article elucidates the intricate mechanisms underlying the dual functions of neutrophils in periodontitis, including respiratory burst, neutrophil extracellular traps (NETs) formation, degranulation, and phagocytosis. By providing a comprehensive understanding of neutrophils involvement in periodontitis, this study aims to empower clinicians with insights into the pathogenesis of periodontitis, thereby fostering novel strategies for its prevention and treatment.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Periodontite
/
Fagocitose
/
Armadilhas Extracelulares
/
Neutrófilos
Idioma:
Zh
Ano de publicação:
2024
Tipo de documento:
Article