Long-term associations of PM1 versus PM2.5 and PM10 with asthma and asthma-related respiratory symptoms in the middle-aged and elderly population.
ERJ Open Res
; 10(4)2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38957167
ABSTRACT
Background:
Few studies have compared the associations between long-term exposures to particulate matters (aerodynamic diameter ≤1, ≤2.5 and ≤10â µm PM1, PM2.5 and PM10, respectively) and asthma and asthma-related respiratory symptoms. The objective of the present study was to compare the strength of the aforementioned associations in middle-aged and elderly adults.Methods:
We calculated the mean 722-day personal exposure estimates of PM1, PM2.5 and PM10 at 1â km×1â km spatial resolution between 2013 and 2019 at individual levels from China High Air Pollutants (CHAP) datasets. Using logistic regression models, we presented the associations as odds ratios and 95% confidence intervals, for each interquartile range (IQR) increase in PM1/PM2.5/PM10 concentration. Asthma denoted a self-reported history of physician-diagnosed asthma or wheezing in the preceding 12â months.Results:
We included 7371 participants in COPD surveillance from Guangdong, China. Each IQR increase in PM1, PM2.5 and PM10 was associated with a greater odds (OR (95% CI)) of asthma (PM1 1.22 (1.02-1.45); PM2.5 1.24 (1.04-1.48); PM10 1.30 (1.07-1.57)), wheeze (PM1 1.27 (1.11-1.44); PM2.5 1.30 (1.14-1.48); PM10 1.34 (1.17-1.55)), persistent cough (PM1 1.33 (1.06-1.66); PM2.5 1.36 (1.09-1.71); PM10 1.31 (1.02-1.68)) and dyspnoea (PM1 2.10 (1.84-2.41); PM2.5 2.17 (1.90-2.48); PM10 2.29 (1.96-2.66)). Sensitivity analysis results were robust after excluding individuals with a family history of allergy. Associations of PM1, PM2.5 and PM10 with asthma and asthma-related respiratory symptoms were slightly stronger in males.Conclusion:
Long-term exposure to PM is associated with increased risks of asthma and asthma-related respiratory symptoms.
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Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article