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Acaricidal activity of Erigeron acer L. root against Haemaphysalis longicornis and phytochemical profiling by liquid chromatography-tandem mass spectrometry.
Banzragchgarav, Orkhon; Ariefta, Nanang R; Umemiya-Shirafuji, Rika; Myagmarsuren, Punsantsogvoo; Battsetseg, Badgar; Battur, Banzragch; Batkhuu, Javzan; Nishikawa, Yoshifumi.
Afiliação
  • Banzragchgarav O; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan.
  • Ariefta NR; Institute of Veterinary Medicine, Mongolian University of Life Sciences, Ulaanbaatar, Mongolia.
  • Umemiya-Shirafuji R; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan.
  • Myagmarsuren P; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan.
  • Battsetseg B; Institute of Veterinary Medicine, Mongolian University of Life Sciences, Ulaanbaatar, Mongolia.
  • Battur B; Institute of Veterinary Medicine, Mongolian University of Life Sciences, Ulaanbaatar, Mongolia.
  • Batkhuu J; Institute of Veterinary Medicine, Mongolian University of Life Sciences, Ulaanbaatar, Mongolia.
  • Nishikawa Y; School of Engineering and Applied Sciences, National University of Mongolia, Ulaanbaatar, Mongolia.
J Vet Med Sci ; 86(8): 897-905, 2024 Aug 02.
Article em En | MEDLINE | ID: mdl-38960665
ABSTRACT
The present study is focused on evaluating acaricidal activity and chemical compositions of Erigeron acer root, which was identified as a promising candidate among fifteen Mongolian plant extracts tested for acaricidal activity. The acaricidal effect was evaluated against Haemaphysalis longicornis, assessed for toxicity to normal human skin fibroblast, and analyzed for its chemical constituents. The acetone extract of E. acer root showed significant activity against H. longicornis, with a lethal concentration (LC50) of 5.31 mg/mL and low toxicity, evidenced by a cytotoxic concentration (CC50) of 267.00 µg/mL. Using liquid chromatography-tandem mass spectrometry and molecular networking, thirteen natural compounds were identified, including pyrrolidines, alkaloids, fatty acids, and flavonoids, highlighting the efficacy of E. acer root extract as an effective acaricide against H. longicornis and offering insights for developing new tick control solutions.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Raízes de Plantas / Erigeron / Espectrometria de Massas em Tandem / Acaricidas / Haemaphysalis longicornis Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Raízes de Plantas / Erigeron / Espectrometria de Massas em Tandem / Acaricidas / Haemaphysalis longicornis Idioma: En Ano de publicação: 2024 Tipo de documento: Article