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Relationship between angiogenesis biomarker endocan and apolipoproteins in patients with acute myocardial infarction.
Hassanpour, Mehdi; Rahbarghazi, Reza; Rezabakhsh, Aysa; Khodavirdilou, Rasa; Darbin, Akbar; Zolali, Elmira; Safaei, Nasser.
Afiliação
  • Hassanpour M; Department of Clinical Biochemistry and Laboratory Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Rahbarghazi R; Shonan Research Institute of Innovative Medicine, Shonan Kamakura General Hospital, Kamakura, Japan.
  • Rezabakhsh A; Department of Applied Cell Science, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Khodavirdilou R; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Darbin A; Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Zolali E; Woman's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Safaei N; Department of Clinical Biochemistry and Laboratory Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Future Cardiol ; : 1-7, 2024 Jul 05.
Article em En | MEDLINE | ID: mdl-38967435
ABSTRACT

Aim:

In the current study, serum levels of endocan in patients attended with ST-elevation myocardial infarction, as well as the possible correlation with apolipoprotein-A1 (APO-A1) and APO-B were investigated. Materials &

methods:

In 80 men, endocan, cTnI, APO-A1, and APO-B levels were measured. Finally, the correlation of endocan with APO-A1, APO-B, and APO-B/ APO-A1 ratio was assessed.

Results:

Significant changes in APO-A1, APO-B, endocan levels, and APO-B/APO-A1 ratio were found in acute myocardial infarction cases compared with the control arm (p < 0.05). In addition, our finding showed a significant correlation between APO-B and endocan levels, but not APO-A.

Conclusion:

High endocan level is an independent indicator of endothelial dysfunction and ischemic cardiovascular conditions, which could be related to APO-B.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article