Intra-articular injection of autologous fat tissue in the treatment of patients with chronic knee pain due to osteoarthritis.
Agri
; 36(3): 162-170, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-38985100
ABSTRACT
OBJECTIVES:
The purpose of this study was to evaluate the safety and efficacy of autologous fat tissue injection into the knee joint for the treatment of osteoarthritis.METHODS:
We reviewed 165 patients who received an intra-articular injection of autologous fat tissue for knee osteoarthritis. The efficacy of the treatment was evaluated at 1, 3, 6, and 12 months follow-up using the Visual Analogue Scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Oxford Knee Score (OKS). Patients with knee arthritis were classified as grades I-IV according to the Kellgren-Lawrence scale (K-L). The clinical and demographic information of the patients, NSAIDs or opioid use, and the side effects related to the procedure were recorded.RESULTS:
There were 62 male and 103 female patients. The mean age was 61.28±11.4 years, and the mean BMI was 26.23±4.49. A significant improvement (p<0.001) was observed in VAS, WOMAC, and OKS values of patients with K-L grade I-III osteoarthritis. Patients with K-L grade IV osteoarthritis showed no statistically significant improvement. No serious complications were observed in the patients. In addition, a statistically significant decrease was found in the daily doses of paracetamol/tramadol and in the number of patients who continued to use NSAIDs after 12 months of follow-up.CONCLUSION:
The results of the study suggest that minimally manipulated autologous fat tissue injections are effective and safe treatment methods for patients with grade I-III knee osteoarthritis. The results may not be satisfactory in severe osteoarthritis due to the limited capabilities.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Medição da Dor
/
Tecido Adiposo
/
Osteoartrite do Joelho
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article