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The precise function of alphaherpesvirus tegument proteins and their interactions during the viral life cycle.
Cui, Yuxi; Wang, Mingshu; Cheng, Anchun; Zhang, Wei; Yang, Qiao; Tian, Bin; Ou, Xumin; Huang, Juan; Wu, Ying; Zhang, Shaqiu; Sun, Di; He, Yu; Zhao, Xinxin; Wu, Zhen; Zhu, Dekang; Jia, Renyong; Chen, Shun; Liu, Mafeng.
Afiliação
  • Cui Y; Engineering Research Center of Southwest Animal Disease Prevention and Control Technology, Ministry of Education of the People's Republic of China, Chengdu, China.
  • Wang M; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu, China.
  • Cheng A; International Joint Research Center for Animal Disease Prevention and Control of Sichuan Province, Chengdu, China.
  • Zhang W; Institute of Veterinary Medicine and Immunology, Sichuan Agricultural University, Chengdu, China.
  • Yang Q; Research Center of Avian Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
  • Tian B; Engineering Research Center of Southwest Animal Disease Prevention and Control Technology, Ministry of Education of the People's Republic of China, Chengdu, China.
  • Ou X; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu, China.
  • Huang J; International Joint Research Center for Animal Disease Prevention and Control of Sichuan Province, Chengdu, China.
  • Wu Y; Institute of Veterinary Medicine and Immunology, Sichuan Agricultural University, Chengdu, China.
  • Zhang S; Research Center of Avian Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
  • Sun D; Engineering Research Center of Southwest Animal Disease Prevention and Control Technology, Ministry of Education of the People's Republic of China, Chengdu, China.
  • He Y; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu, China.
  • Zhao X; International Joint Research Center for Animal Disease Prevention and Control of Sichuan Province, Chengdu, China.
  • Wu Z; Institute of Veterinary Medicine and Immunology, Sichuan Agricultural University, Chengdu, China.
  • Zhu D; Research Center of Avian Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.
  • Jia R; Sinopharm Yangzhou VAC Biological Engineering Co., Ltd., Yangzhou, China.
  • Chen S; Engineering Research Center of Southwest Animal Disease Prevention and Control Technology, Ministry of Education of the People's Republic of China, Chengdu, China.
  • Liu M; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu, China.
Front Microbiol ; 15: 1431672, 2024.
Article em En | MEDLINE | ID: mdl-39015737
ABSTRACT
Alphaherpesvirus is a widespread pathogen that causes diverse diseases in humans and animals and can severely damage host health. Alphaherpesvirus particles comprise a DNA core, capsid, tegument and envelope; the tegument is located between the nuclear capsid and envelope. According to biochemical and proteomic analyses of alphaherpesvirus particles, the tegument contains at least 24 viral proteins and plays an important role in the alphaherpesvirus life cycle. This article reviews the important role of tegument proteins and their interactions during the viral life cycle to provide a reference and inspiration for understanding alphaherpesvirus infection pathogenesis and identifying new antiviral strategies.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article