Acupuncture for constipation in Parkinson's disease: A systematic review and meta-analysis of randomized controlled trials.
Medicine (Baltimore)
; 103(29): e38937, 2024 Jul 19.
Article
em En
| MEDLINE
| ID: mdl-39029044
ABSTRACT
BACKGROUND:
Parkinson's disease (PD) is the second most common neurological disease worldwide, and there is a potential interaction between PD and constipation. PD constipation often causes significant trouble for patients and seriously affects their quality of life. Acupuncture is widely used for treating constipation and has been clinically proven. However, it is unclear whether the current evidence is sufficient to support acupuncture to improve PD constipation.METHODS:
We searched the Cochrane Central Register of Controlled Trials, Embase, PubMed, Web of Science, China National Knowledge Infrastructure, Wan Fang Data Knowledge Service Platform, and Chinese Scientific Journal Database (VIP database) for randomized controlled trials from inception through July 1, 2023. Randomized controlled trials (RCTs) included acupuncture, sham acupuncture, and medication for PD constipation. Stata 16.0 software and Cochrane RoB2.0 were used for data processing and migration risk analysis.RESULTS:
The 11 studies included a total of 960 patients. The results showed that acupuncture or acupuncture combined with conventional treatment seemed to have advantages in improving complete spontaneous bowel movements (WMD 1.49, 95% CI 0.86, 2.11; Pâ <â .00001), Patient-Assessment of Constipation Quality of Life questionnaire (WMD -11.83, 95% CI -15.67, -7.99; Pâ <â .00001), the chronic constipation severity scale (CCS) (SMD -0.99, 95% CI -1.40, -0.58; Pâ <â .01), and c(RRP) (WMD 2.13, 95% CI 0.44, 3.82; Pâ <â .05).CONCLUSION:
The present results show that compared with conventional treatment, acupuncture combined with conventional treatment seems to increase the number of spontaneous defecations in PD patients, improve quality of life, increase rectal resting pressure, and alleviate the severity of chronic constipation. Thus, acupuncture has the potential to treat PD constipation. However, due to the study's limitations, higher-quality RCTs are needed for verification.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Doença de Parkinson
/
Qualidade de Vida
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Terapia por Acupuntura
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Ensaios Clínicos Controlados Aleatórios como Assunto
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Constipação Intestinal
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article