3D Spheroid and Organoid Models to Study Neuroinfection of RNA Viruses.
Methods Mol Biol
; 2824: 409-424, 2024.
Article
em En
| MEDLINE
| ID: mdl-39039427
ABSTRACT
Three-dimensional culture models of the brain enable the study of neuroinfection in the context of a complex interconnected cell matrix. Depending on the differentiation status of the neural cells, two models exist 3D spheroids also called neurospheres and cerebral organoids. Here, we describe the preparation of 3D spheroids and cerebral organoids and give an outlook on their usage to study Rift Valley fever virus and other neurotropic viruses.
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Base de dados:
MEDLINE
Assunto principal:
Organoides
/
Esferoides Celulares
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article